42923-79-5, 7-Nitro-1,2,3,4-tetrahydroisoquinoline is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of 8 (5.4g, 26mmol), Et3N (9. 8mL, 70mmol) and acetic anhydride (5. 0ml, 51mmol) in CH2C12 (70mL) is stirred at reflux temperature for 1 hour, cooled, and the reaction mixture is poured onto ice. The resulting solution is extracted three times with methylene chloride. The organic layer is dried over sodium sulfate and evaporated in vacuo. The residue is chromatographed on flash silica gel to give 5.3g of 13 (94% YIELD). 1H NMR (300MHz, CDCl3) delta 8.05-8. 03 (2H, M, H-6,8), 7.43-7. 30 (1H, M, H-5), 4.83 (1.2H, s, ArCH2N), 4.72 (0.8H, s, ArCH2N), 3.87 (0.8H, t, ArCH2CH2N), 3.74 (1.2H, t, ArCH2CH2N), 3.02 (1.2H, t, ArCH2CH2N), 2.95 (0.8H, t, ArCH2CH2N), 2.21 (1.2H, s, COCH3), 2.20 (1.8H, s, COCH3).
42923-79-5 7-Nitro-1,2,3,4-tetrahydroisoquinoline 6424833, atetrahydroisoquinoline compound, is more and more widely used in various.
Reference£º
Patent; BUOLAMWINI, John, K,; WO2004/60902; (2004); A2;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem