42923-79-5, 7-Nitro-1,2,3,4-tetrahydroisoquinoline is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stined solution of 7-nitro-2 ,3-dihydro- 1 H-spiro[cyclopropane- 1,4- isoquinoline] (500 mg, 2.45 mmol) in DMF (5 mL) was added K2C03 (1.55 g, 11.23 mmol) at 0 C. After 5 mins, methanesulfonyl chloride (0.4 mL, 5.62 mmol) was added at 0 C, and the reaction was stined at RT for 3 h. The reaction was diluted with water and extracted with EA (2 x 30 mL). The combined organic layers were washed with water (15 mL), dried (Na2SO4), and concentrated. The crude was triturated with pentane to afford 2- (methylsulfonyl)-7-nitro-1,2,3,4-tetrahydroisoquinoline (505 mg, 70%) as a pale yellow solid. MS (ESI) mlz 257.3 [M+H].
As the paragraph descriping shows that 42923-79-5 is playing an increasingly important role.
Reference£º
Patent; ZENO ROYALTIES & MILESTONES, LLC; HUANG, Peter, Qinhua; BOREN, Brant, Clayton; BUNKER, Kevin, Duane; LIU, Hui; PALIWAL, Sunil; (99 pag.)WO2019/28008; (2019); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem