Brief introduction of 877861-62-6

As the paragraph descriping shows that 877861-62-6 is playing an increasingly important role.

877861-62-6, Methyl 1,2,3,4-tetrahydroisoquinoline-6-carboxylate hydrochloride is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

877861-62-6, Step 1 : Preparation of 2-(1 ,1-dimethylethyl) 6-methyl 3,4-dihvdro-2,6(1/-/)-isoquinoline- dicarboxylate; To a solution of methyl 1 ,2,3,4-tetrahydroisoquinoline-6-carboxylate hydrochloride(0.30 g, 1.32 mmol) in dioxane/H2O (2:1 , 5 ml.) was added 1 N NaOH (1.97 ml_, 1.97 mmol) followed by BoC2O (0.43 g, 1.97 mmol). The reaction was stirred at room temperature for 1 hour, at which time LCMS indicated complete conversion to product.The reaction was poured into H2O (10 ml.) and extracted with CH2CI2 (3×10 ml_). The organics were dried (Na2SO4) and evacuated. The crude carbamate was used directly in the next step.

As the paragraph descriping shows that 877861-62-6 is playing an increasingly important role.

Reference£º
Patent; SMITHKLINE BEECHAM CORPORATION; WO2009/49154; (2009); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem