1029689-82-4, Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate hydrochloride is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of methyl l,2,3,4-tetrahydroisoquinoline-8-carboxylate hydrochloride (12.37 g) and Example 1.1.11 (15 g) in dimethyl sulfoxide (100 mL) was added N,N-diisopropylethylamine (12 mL). The mixture was stirred at 50C for 24 hours. The mixture was then diluted with ethyl acetate (500 mL), washed with water and brine, and dried over NaaSOzi. Filtration and evaporation of the solvent gave a residue that was purified by silica gel chromatography, eluting with 20% ethyl acetate in heptane, to give the title compound. MS (ESI) m/e 448.4 (M+H)+.
1029689-82-4, 1029689-82-4 Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate hydrochloride 45074000, atetrahydroisoquinoline compound, is more and more widely used in various.
Reference£º
Patent; ABBVIE INC.; BOGHAERT, Erwin R.; ACKLER, Scott L.; TAO, Zhi-Fu; WANG, Xilu; DOHERTY, George; MARIN, Violeta L.; SULLIVAN, Gerard M.; SONG, Xiaohong; KUNZER, Aaron R.; WELCH, Dennie S.; BRUNCKO, Milan; JUDD, Andrew S.; SOUERS, Andrew J.; (276 pag.)WO2016/94505; (2016); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem