215798-19-9, 6-Bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,215798-19-9
Step B: Acryloyl chloride (1.0 g, 11 mmol, 1.2 eq.) was added to a solution of 6-bromo-I, 2,3,4-tetrahydroisoquinolinehydrochloride (2.0 g, 9 mmol, 1 eq.) and triethylamine (2.9 g, 28 mmol, 3.0 eq) in DCM (40 mL) at 0C. The mixturewas stirred at 15C for 14 hours. The reaction mixture was poured into water (30 mL) and extracted with DCM (50mL 3 2). The organic phase was dried with anhydrous Na2SO4 and concentrated in vacuum. The residue waspurified by column chromatography to give 1-(6-bromo-1,2,3,4-tetrahydroisoquinolin-yl)propyl-2-en-1-one (1.4 g, 5mmol, 56% yield) as a yellow oil. MS (ESI) m/z: 266 (M + 1).
The synthetic route of 215798-19-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; CHEN, Shuhui; DING, Charles Z.; YAN, Xiaobing; HUANG, Wei; HU, Guoping; LI, Jian; ZHANG, Xiquan; YANG, Ling; XU, Hongjiang; (121 pag.)EP3248968; (2017); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem