Downstream synthetic route of 42923-77-3

42923-77-3, As the paragraph descriping shows that 42923-77-3 is playing an increasingly important role.

42923-77-3, 6-Methoxy-1,2,3,4-tetrahydroisoquinoline is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a 50 mL Erlenmeyer flask, 190 mg (0.22 mmol) of troxerutin and glutaryl vinyl ether was added,359 mg (2.20 mmol) of 6-methoxy-1,2,3,4-tetrahydroisoquinoline, [TOMA] [Tf2N](N-hexylpyridine bistrifluoromethanesulfonimide salt) 20mL,60 air bath oscillator, 150rpm constant temperature oscillation, the reaction 30h. Ethyl acetate extraction, the extract was concentrated, column chromatography The product was obtained and the eluent was ethyl acetate / methanol / water (20/3/1, v / v) to give the troxerutamide derivative containing methoxytetrahydroisoquinoline. The product was a light yellow solid, 155 mg, 71% yield.

42923-77-3, As the paragraph descriping shows that 42923-77-3 is playing an increasingly important role.

Reference£º
Patent; Henan University of Technology; Xiao Yongmei; Mao Pu; Yang Shuoye; Yang Liangru; Qu Lingbo; Yuan Jinwei; (17 pag.)CN107163096; (2017); A;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem