42923-79-5, 7-Nitro-1,2,3,4-tetrahydroisoquinoline is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A mixture of the required 1,2,3,4-tetrahydroisoquinoline derivative (1 equivalent), NaHCO3 (2 equivalents), and the appropriate substituted fluoro- or chlorobenzoic acid (1 equivalent) was heated at reflux in a mixture of ethanol : water (2:1) with stirring (15 hours). The ethanol was evaporated and the residue was poured onto ice and extracted several times with CH2Cl2. The combined organic layers were discarded and the aqueous layer acidified with concentrated hydrochloric acid solution until pH 2 yielding a solid. The solid was collected and dried in a vacuum dessicator over P2O5 giving the crude N-(carboxy-nitroaryl)-1,2,3,4-tetrahydroisoquinoline derivative.
42923-79-5, As the paragraph descriping shows that 42923-79-5 is playing an increasingly important role.
Reference£º
Article; Burke, Philip J.; Chun Wong, Lai; Jenkins, Terence C.; Knox, Richard J.; Stanforth, Stephen P.; Bioorganic and Medicinal Chemistry Letters; vol. 21; 24; (2011); p. 7447 – 7450;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem