Downstream synthetic route of 57060-88-5

As the paragraph descriping shows that 57060-88-5 is playing an increasingly important role.

57060-88-5, Methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,57060-88-5

(B) Methyl 2-[N2 -(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylate To a stirred solution of 1.8 g of methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride and 8 ml of triethylamine in 50 ml of chloroform which was cooled in an ice bath, there was carefully added N2 -(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl chloride hydrochloride obtained above. The reaction mixture was allowed to stand overnight at room temperature. The reaction mixture was washed twice with 50 ml of saturated sodium chloride solution and evaporated to dryness. The residue was dissolved in water-ethanol and ajusted to pH 12 with 5N NaOH solution at a temperature below 0 C to precipitate a solid. This was collected by filtration to give 3 g of methyl 2-[N2 -(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylate. I.R. (KBr): 3,350, 1,740, 1,640, 1,260, 1,160 cm-1. Analysis-Calcd. for C29 H35 O7 N5 S1 (percent): C, 58.27; H, 5.90; N, 11.72. Found (percent): C, 58.45; H, 6.03; N, 11.53.

As the paragraph descriping shows that 57060-88-5 is playing an increasingly important role.

Reference£º
Patent; Mitsubishi Chemical Industries Ltd.; Okamoto; Shosuke; US4104392; (1978); A;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem