1029689-82-4, As the paragraph descriping shows that 1029689-82-4 is playing an increasingly important role.
1029689-82-4, Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate hydrochloride is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 11; Synthesis of methyl 2-f6.7.8-trimethoxyquinazoline-4-vD- 1.2.3.4- tetrahycroisoquinoline-8-carboxylate; [00214] Methyl 1, 2,3 ,4-tetrahydroisoquinoline-8-carboxy late hydrochloride (268 mg,1.18 mmol), N,N-dimethylacetamide (14.6 mL, 0.158 mol), 4-chloro-6,7,8- trimethoxyquinazoline (300 mg, 1.18 mol), sodium iodide (80 mg, 0.0005 mol), and potassium carbonate (407 mg, 02.94 mol) were combined and heated at 160 0C for 12 hr. The crude product was purified by preparative HPLC with a C 18 column using acetonitrile: water (with 0.1% formic acid) as eluant with a gradient from 10:90 (v/v) to 80:20 (v/v) at a flow rate of 45 mL/min to give methyl 2-(6,7,8-trimethoxyquinazoline-4-yl)- l,2,3,4-tetrahycroisoquinoline-8-carboxylate.
1029689-82-4, As the paragraph descriping shows that 1029689-82-4 is playing an increasingly important role.
Reference£º
Patent; AMGEN INC.; MEMORY PHARMACEUTICALS CORPORATION; WO2007/103260; (2007); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem