As a common heterocyclic compound, it belongs to tetrahydroisoquinoline compound, name is 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride, and cas is 57196-62-0, its synthesis route is as follows.,57196-62-0
a) 1 ,2,3 ,4-Tetrahvdro-isoquinolin-6-ol hydrobromide6-Methoxy-l,2,3,4-tetrahydro-isoquinoline hydrochloride, prepared as in WO 2004/26305, (18.9 g, 94 mmol) in 48% aqueous hydrobromic acid was heated at 100 C for 12 h and then cooled to 0 C. The solid was filtered off, washed with t-butyl methyl ether and dried. Yield= 17.1 g (79%) APCI-MS m/z: 150 [M+H+];1HNMR (400 MHz, DMSOd6) delta2.91 (t, 2H), 3.27 – 3.35 (m, 2H), 4.13 (t, 2H), 4.52 (s, IH), 6.59 (d, IH), 6.66 (dd, IH), 7.00 (d, IH), 9.07 (s, 2H) ppm.
With the complex challenges of chemical substances, we look forward to future research findings about 57196-62-0,belong tetrahydroisoquinoline compound
Reference£º
Patent; ASTRAZENECA AB; WO2006/65215; (2006); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem