Analyzing the synthesis route of 81237-69-6

As the paragraph descriping shows that 81237-69-6 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.81237-69-6,5-Bromo-1,2,3,4-tetrahydroisoquinoline,as a common compound, the synthetic route is as follows.,81237-69-6

Intermediate 24A. 5-Bromo-l,4-dihydroisoquinoline: 5-Bromo-l,2,3,4- tetrahydroisoquinoline (0.500 g, 2.36 mmol) in DCM (25 mL) was treated with manganese dioxide (3.69 g, 42.4 mmol). After 15 h, the reaction mixture was filtered through a plug of CELITE and filtrate concentrated. The imine was carried forward as is. MS (ESI) m/z: 209.8 (M+H)+.

As the paragraph descriping shows that 81237-69-6 is playing an increasingly important role.

Reference£º
Patent; BRISTOL-MYERS SQUIBB COMPANY; PINTO, Donald J.P.; CLARK, Charles G.; SMITH, II, Leon M.; ORWAT, Michael J.; JEON, Yoon; CORTE, James R.; WO2014/160668; (2014); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem