Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Computed Properties of C10H13N. Introducing a new discovery about 1612-65-3, Name is 2-Methyl-1,2,3,4-tetrahydroisoquinoline
Nitrogen-containing remote functionalised organolithium compounds by reductive opening of five- and six-membered heterocycles
The reaction of different five- or six-membered nitrogen- containing heterocycles such as N-isopropyl-2-phenylpyrrolidine (1), N-phenyl-3-pyrroline (6), N-phenylisoindoline (10), N- phenyltetrahydroisoquinoline (13) and N- methyltetrahydroisoquinoline (19) with an excess of lithium powder ad a catalytic amount of DTBB (4.5 mol %), followed by treatment with electrophiles [H2O, D2O, MeI, CH2=CHCH2Br, Pr(i)CHO,Bu(t)CHO, PhCHO, Me2CO, Pr(n)COMe, PhCOMe, (CH2)4CO, (CH2)5CO, CO2] and final hydrolysis gives a wide series of functionalised amines 3, 8, 9, 12 and 19, the key step in the process, being the reductive opening of the starting material giving a dianionic remote functionalised organolithium compound.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C10H13N, you can also check out more blogs about1612-65-3
Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem