One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of (S)-Methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 78183-55-8, Name is (S)-Methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride, molecular formula is C11H14ClNO2
Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.
All previously reported CAAX-based farnesyltransferase inhibitors contain a thiol functionality. We report that attachment of the 4-imidazolyl group, via 1-, 2-, or 3-carbon alkyl or alkanoyl spacers, to Val-Tic-Met or tLeu-Tic-Gln provides potent FT inhibitors. (R*)-N-[[1,2,3,4-Tetrahydro-2-[N-[2-(1H-imidazol-4-yl)ethyl] -L-valyl]-3-isoquinolinyl]carbonyl]-L-methionine ([imidazol- 4-yl-ethyl]-Val-Tic-Met), with FT IC50 = 0.79 nM, displayed potent cell activity in the absence of prodrug formation (SAG EC50 = 3.8 muM).
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Quality Control of (S)-Methyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 78183-55-8
Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem