1745-07-9, Name is 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline, belongs to tetrahydroisoquinoline compound, is a common compound. Formula: C11H15NO2In an article, once mentioned the new application about 1745-07-9.
DDQ-promoted mild and efficient metal-free oxidative alpha-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines
A mild and highly efficient metal-free oxidative alpha-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) has been accomplished at an ambient temperature via DDQ oxidation and subsequent trapping of N-acyl/sulfonyl iminium ions with (n-Bu)3SnCN. Employing readily removable N-acyl/sulfonyl groups as protecting groups rather than N-aryl ones enables a wide range of applications in natural product synthesis. The synthetic utility of the method was illustrated using a short and efficient formal total synthesis of (¡À)-calycotomine in three steps.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 1745-07-9
Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem