Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of 6-Bromo-1,2,3,4-tetrahydroisoquinoline. Introducing a new discovery about 226942-29-6, Name is 6-Bromo-1,2,3,4-tetrahydroisoquinoline
Copper-catalyzed aerobic cyclizations of tetrahydroisoquinolines with bromoketones and alkenes for the synthesis of 5,6-dihydropyrrolo[2,1-a] isoquinolines
A new copper-catalyzed oxidative cyclization protocol was developed for the synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines via a three-component reaction of tetrahydroisoquinolines with bromoketones and electron-deficient alkenes with air as a terminal oxidant. A variety of functional groups survived under the reaction conditions and the target products were obtained in good yields. This reaction features such advantages as eco-friendly reaction conditions, a simplified operation process and a broad substrate scope.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 6-Bromo-1,2,3,4-tetrahydroisoquinoline, you can also check out more blogs about226942-29-6
Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem