Synthetic Route of 1745-07-9, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1745-07-9, Name is 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline, molecular formula is C11H15NO2. In a Article£¬once mentioned of 1745-07-9
Synthesis and in-vitro antimycobacterial evaluation of 1-(cyclopropyl/2,4- difluorophenyl/tert-butyl)-1,4-dihydro-8-methyl-6-nitro-4-oxo-7-(substituted secondary amino)quinoline-3-carboxylic acids
Fifty one newer -(cyclopropyl/2,4-difluorophenyl/tert-butyl)-1,4-dihydro-8- methyl-6-nitro-4-oxo-7-(substituted secondary amino)quinoline-3-carboxylic acids were synthesized from 1,3-dichloro-2-methylbenzene and evaluated for in-vitro antimycobacterial activities against Mycobacterium tuberculosis H37Rv (MTB), multi-drug resistant Mycobacterium tuberculosis (MDR-TB), and Mycobacte-rium smegmatis (MC2). Among the synthesized compounds, 1-cyclopropyl-1,4-dihydro-7-(3,4-dihy-dro-6,7-dimethoxyisoquinolin-2(1H)-yl) -8-methyl-6-nitro-4-oxoquinoline-3-carboxylic acid 9p was found to be the most active compound in vitro with a MIC value of 0.39 M against MTB. Against MDR-TB, compound -(2-carboxy-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)-1- cyclopropyl-1,4-dihydro-8-methyl-6-nitro-4-oxoquinoline-3-carboxylic acid 9n was found to be the most active with a MIC value of 0.09 M.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 1745-07-9. In my other articles, you can also check out more blogs about 1745-07-9
Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem