Archives for Chemistry Experiments of 3340-78-1

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Cobalt-catalyzed aerobic oxidative Povarov reaction of tertiary anilines with dihydrofuran for the synthesis of hexahydrofuroquinolines

A simple and efficient cobalt-catalyzed aerobic oxidative dehydrogenative Povarov reaction of tertiary anilines with dihydrofuran has been developed for the synthesis of hexahydrofuro[3,2-c]quinolines. The one-electron-oxidation involved reaction is performed under mild conditions and only requires simple cobalt salts as a catalyst and dioxygen as a terminal oxidant.

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Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem