In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 43207-78-9, name is 7-Methoxy-1,2,3,4-tetrahydroisoquinoline, introducing its new discovery. Safety of 7-Methoxy-1,2,3,4-tetrahydroisoquinoline
DDQ-promoted mild and efficient metal-free oxidative alpha-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines
A mild and highly efficient metal-free oxidative alpha-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) has been accomplished at an ambient temperature via DDQ oxidation and subsequent trapping of N-acyl/sulfonyl iminium ions with (n-Bu)3SnCN. Employing readily removable N-acyl/sulfonyl groups as protecting groups rather than N-aryl ones enables a wide range of applications in natural product synthesis. The synthetic utility of the method was illustrated using a short and efficient formal total synthesis of (±)-calycotomine in three steps.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 43207-78-9, and how the biochemistry of the body works.Safety of 7-Methoxy-1,2,3,4-tetrahydroisoquinoline
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem