Final Thoughts on Chemistry for 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid

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Selective Hydrodeoxygenation of 2-Furancarboxylic Acid to Valeric Acid over Molybdenum-Oxide-Modified Platinum Catalyst

2-Furancarboxylic acid (FCA), produced by oxidation of furfural, is rarely used as a platform molecule. Metal-oxide-supported Pt-MoOx catalysts were effective for hydrodeoxygenation of FCA to valeric acid (VA) in water solvent. The highest VA yield is 51% over Pt-MoOx/TiO2 catalyst under 1.5 MPa H2 at 413 K. Other metal combinations (M-MoOx, M = Rh, Pd, Ru, Ir, Au, none; Pt-M’Ox, M’= V, W, Re, none) showed very low VA yield. This catalyst system was applicable to the hydrodeoxygenation of 2,5-furandicarboxylic acid (FDCA), and adipic acid (AA) was obtained with 21% yield at 473 K.

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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem