New Advances in Chemical Research in 2021. In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 118864-75-8, name is (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, introducing its new discovery. Reference of 118864-75-8
The invention discloses a succinic acid thorley that new raw materials of synthesizing process, respectively in order to 2 – phenethylamine and 3 – synthesizing hydrochloride as the starting material synthetic fragment A, fragment B, the occurrence of the condensation reaction produced Solley that new, by succinic acid and get thorley that new, characterized in that using straight chain paraffins and water is used as the reaction solvent, alkali metal hydroxide or carbonate, hydrogencarbonate for capture, phenethylamine takes acylation reaction with benzoyl chloride is not soluble in the reaction solvent of solid precipitation fragment A intermediate 1, after treatment directly during the filtering; fragment A isomer, using dimethyl sulfoxide as solvent, alkali metal hydroxide catalytic racemic, the by-product isomer can be recycled; fragment of B 2nd step treatment after the reaction, the conventional vacuum distillation method to obtain a high purity, high yield of 3 – acetoxy quinine acetic acid salt, the invention provides a high yield, is suitable for industrial mass production, economic and environmental protection new synthesis process. (by machine translation)
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 118864-75-8
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem