New research progress on 1745-07-9 in 2021. name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1745-07-9, molcular formula is C11H15NO2, introducing its new discovery.
A series of 1,2,3,4-tetrahydroisoquinoline substituted 2H-pyranones and 1,3-teraryls have been synthesized taking berberine as lead and evaluated for glucose uptake stimulatory effect in skeletal muscle cells. Compound 5d showed significant stimulation of glucose uptake in a concentration-dependent manner with maximum stimulation (2.7 fold) at 10 muM in L6 skeletal muscle cells. The compound was found to have synergistic effect with insulin, and mechanistic studies revealed the PI-3-K-mediated signaling pathway for stimulation of glucose uptake in skeletal muscle cells.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 1745-07-9, help many people in the next few years.name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem