Interesting scientific research on 15227-42-6

Here is a brief introduction to this compound(15227-42-6)Quality Control of cis-Dichlorobis(pyridine)platinum(II), if you want to know about other compounds related to this compound(15227-42-6), you can read my other articles.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Supramolecular Nanoencapsulation as a Tool: Solubilization of the Anticancer Drug trans-Dichloro(dipyridine)platinum(II) by Complexation with β-Cyclodextrin, published in 2008-04-30, which mentions a compound: 15227-42-6, mainly applied to beta cyclodextrin trans dichlorodipyridine platinum complex nanoencapsulation solubilization anticancer, Quality Control of cis-Dichlorobis(pyridine)platinum(II).

A novel, water-soluble trans-platinum complex was synthesized by inclusion complexation with β-cyclodextrin. The complexation was confirmed by 1H NMR, FT-IR, TGA, and XRD as well as by SEM and EDX. As the precursor complex is not water-soluble, it is difficult to employ it for biol. applications. Here, we report that the encapsulation with cyclodextrin allowed to solubilize the complex to a solubility value of 1.6 mg/mL. Moreover, the cytotoxicity in vitro of the novel inclusion complex indicated a much higher activity after encapsulation.

Here is a brief introduction to this compound(15227-42-6)Quality Control of cis-Dichlorobis(pyridine)platinum(II), if you want to know about other compounds related to this compound(15227-42-6), you can read my other articles.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem