Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of the Serbian Chemical Society called Novel (-)-goniofufurone mimics: Synthesis, antiproliferative activity and SAR analysis, Author is Zelenovic, Bojana Sreco; Kekezovic, Sladjana; Popsavin, Mirjana; Kojic, Vesna; Benedekovic, Goran; Popsavin, Velimir, which mentions a compound: 693-67-4, SMILESS is CCCCCCCCCCCBr, Molecular C11H23Br, Application In Synthesis of 1-Bromoundecane.
Divergent syntheses of novel (-)-goniofufurone mimics with an alko-xymethyl group as the side chain have been accomplished from D-glucose in nine synthetic steps and in overall yields 6.7-8.7%. Their in vitro antiproliferative activity was evaluated against eight human tumor cell lines as well as a single normal cell line. All analogs demonstrated powerful to good antiproliferative effects toward all malignant cell lines under evaluation. Against the HL-60 cell line, all mimics showed increased activities being 27- to 1604-fold more potent than the lead compound, (-)-goniofufurone. Remarkably, the majority of synthesized analogs displayed higher or similar activity to the com. antitumor agent doxorubicin (DOX) against A549 cell line. The most potent compound exhibited 196-fold stronger cytotoxicity than DOX in the culture of this cell line.
In some applications, this compound(693-67-4)Application In Synthesis of 1-Bromoundecane is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem