The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 3-(2,5-Dichloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole, is researched, Molecular C18H11Cl2N3O2S, CAS is 882562-40-5, about Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors, the main research direction is aminopyrimidine derivative preparation antiinflammatory JNK inhibitor.HPLC of Formula: 882562-40-5.
The development of a series of aminopyrimidines, e.g., I, as inhibitors of c-Jun N-terminal kinases is described. The synthesis, in vitro inhibitory values for JNK1, JNK2 and CDK2, and the in vitro inhibitory value for a c-Jun cellular assay were discussed.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem