The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: cis-Dichlorobis(pyridine)platinum(II)(SMILESS: [Cl-][Pt+2]([N]1=CC=CC=C1)([Cl-])[N]2=CC=CC=C2,cas:15227-42-6) is researched.Application of 693-67-4. The article 《Antitumor and antimitogenic properties of cis-dichloro(dipyridine)platinum(II)》 in relation to this compound, is published in Cancer Research. Let’s take a look at the latest research on this compound (cas:15227-42-6).
cis-Dichloro(dipyridine)platinum(II) (I) showed less potent antitumor and antimitogenic activity than previously studied cis-[Pt(NH3)2Cl2] (Rosenberg, B.; Van Camp, L., 1970). However in preliminary experiments, I was also less toxic to mice than the inorganic complex. I inhibited the growth of Escherichia coli. I increased the survival time of mice bearing Ehrlich ascites tumor; in vitro, I also inhibited protein and nucleic acid synthesis by tumors. I inhibited DNA synthesis in phytohemagglutinin-stimulated cultures of human lymphocytes.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem