Interesting scientific research on 15227-42-6

In addition to the literature in the link below, there is a lot of literature about this compound(cis-Dichlorobis(pyridine)platinum(II))Application of 15227-42-6, illustrating the importance and wide applicability of this compound(15227-42-6).

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Density functional theory and surface enhanced Raman spectroscopy characterization of novel platinum drugs, published in 2002, which mentions a compound: 15227-42-6, mainly applied to anticancer platinum complex density functional theory; Raman spectroscopy anticancer platinum complex, Application of 15227-42-6.

There is considerable interest in the development of novel platinum-based anticancer drugs that overcome the disadvantages associated with the widely used drug cisplatin, which are its inactivity against some types of tumors and its toxic side effects. In this study we show the suitability of normal Raman spectroscopy (NRS) and surface enhanced Raman spectroscopy (SERS), assisted by d. functional theor. (DFT) calculations, for the characterization of Pt complexes. The Pt complexes studied include the established drugs cisplatin and carboplatin, as well as five novel Pt complexes with anticancer activity. DFT calculations at the B3LYP/LanL2DZ level are a good prediction of the exptl. NRS spectra of small and medium sized Pt complexes. The use of SERS allows the investigation of Pt complexes at physiol. concentrations, and the binding strengths of the different ligands can be determined The formation of pos. charged hydrolysis products may be necessary for SERS activity. The existing group in the hydrolysis reaction can be identified.

In addition to the literature in the link below, there is a lot of literature about this compound(cis-Dichlorobis(pyridine)platinum(II))Application of 15227-42-6, illustrating the importance and wide applicability of this compound(15227-42-6).

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem