The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-Bromoundecane(SMILESS: CCCCCCCCCCCBr,cas:693-67-4) is researched.Recommanded Product: Picolinamide. The article 《A simple and efficient approach for the synthesis of a novel class aliphatic 1,3,4-thiadiazol-2(3H)-one derivatives via intramolecular nucleophilic substitution reaction》 in relation to this compound, is published in Synthetic Communications. Let’s take a look at the latest research on this compound (cas:693-67-4).
In this study, a new series of substituted 1,3,4-thiadiazol-2(3H)-one derivatives I [R = Et, CH2CH=CH2, cyclohexylmethyl, etc.] was synthesized in yields ranging from 42 to 70% via reaction of alkyl bromides with 1-(4-chlorophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)thio)ethanol with an interesting mechanism that involved internal nucleophilic substitution followed by an SN2-type nucleophilic substitution. First, 1-(4-chlorophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)thio)ethanone was synthesized from the reaction of 5-methyl-1,3,4-thiadiazole-2-thiol with 2-bromo-1-(4-chlorophenyl)ethanone which underwent reduction to afford 1-(4-chlorophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)thio)ethanol. The advantages of this protocol were synthesis of target compounds under mild conditions using simple synthetic methods and obtaining them without phosgene.
In addition to the literature in the link below, there is a lot of literature about this compound(1-Bromoundecane)COA of Formula: C11H23Br, illustrating the importance and wide applicability of this compound(693-67-4).
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem