Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1452-77-3, is researched, SMILESS is O=C(N)C1=NC=CC=C1, Molecular C6H6N2OJournal, Polyhedron called Structural and electrochemical properties of two novel CdX2 (X = Br, I) picolinamide complexes, Author is Jadresko, Dijana; Markovic, Berislav; Medvidovic-Kosanovic, Martina; Matkovic-Calogovic, Dubravka; Szechenyi, Aleksandar; Pockaj, Marta; Balic, Tomislav; Popovic, Zora, the main research direction is cadmium bromine iodine picolinamide complex preparation thermal stability electrochem; crystal structure cadmium bromine iodine picolinamide complex.Safety of Picolinamide.
Two novel discrete cadmium(II) complexes, namely [CdBr2(pia)2] (1) and [CdI2(pia)2] (2) were prepared by reactions of aqueous solutions of CdX2 (X = Br, I) salts with picolinamide (pia) in the 2:1 ligand to metal stoichiometric ratio. Both compounds were characterized by elemental anal., IR-spectroscopy, TG/DSC analyses and electrochem. methods. The electrochem. characteristics of both ligand (pia) and prepared complexes were studied by cyclic and (cyclic) square-wave voltammetry, on a static mercury drop electrode (SMDE), in aqueous media over a wide pH range. The mol. and crystal structure of the compounds was determined by the single crystal X-ray diffraction method. X-ray structure anal. of 1 and 2 have shown that the compounds are isostructural with minor differences in the bond angles of the coordination sphere. In both compounds the Cd(II) ion is coordinated by two halide atoms and two mutually orthogonal picolinamide ligands that act as N,O-chelators in a distorted octahedral arrangement. In the crystal structure, the mols. of 1 and 2 are primarily linked via strong head-to-head amide hydrogen bond interactions forming dimers. In 1 the adjacent dimers are connected via N-H···Br hydrogen bonds and offset face to face π···π interactions that involve pyridine rings, while in the structure of 2, the dimers are connected via C-H···O, C-H···N and N-H···I hydrogen bonds into the final 3D structure. The intermol. interactions in both crystal structures were further studied by Hirshfeld surface anal. Electrochem. anal. of 2-picolinamide indicates the irreversible nature of its electro-reduction reaction on SMDE at pH 2. To provide better insight into the redox mechanism and electrokinetic properties of 2-picolinamide, the study of the effect of signal frequency on CSWV response was carried out, too. The electrochem. reduction of complex 2 involves two electron transfer reactions at -0.55 V and -0.83 V, indicating two redox active centers in the mol., while complex 1 appears to be apparently electro-inactive in the studied potential range.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem