In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Density functional theory and surface enhanced Raman spectroscopy characterization of novel platinum drugs, published in 2002, which mentions a compound: 15227-42-6, Name is cis-Dichlorobis(pyridine)platinum(II), Molecular C10H10Cl2N2Pt, Recommanded Product: cis-Dichlorobis(pyridine)platinum(II).
There is considerable interest in the development of novel platinum-based anticancer drugs that overcome the disadvantages associated with the widely used drug cisplatin, which are its inactivity against some types of tumors and its toxic side effects. In this study we show the suitability of normal Raman spectroscopy (NRS) and surface enhanced Raman spectroscopy (SERS), assisted by d. functional theor. (DFT) calculations, for the characterization of Pt complexes. The Pt complexes studied include the established drugs cisplatin and carboplatin, as well as five novel Pt complexes with anticancer activity. DFT calculations at the B3LYP/LanL2DZ level are a good prediction of the exptl. NRS spectra of small and medium sized Pt complexes. The use of SERS allows the investigation of Pt complexes at physiol. concentrations, and the binding strengths of the different ligands can be determined The formation of pos. charged hydrolysis products may be necessary for SERS activity. The existing group in the hydrolysis reaction can be identified.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem