Challa, Prathap; Venkata Rao, M.; Nagaiah, P.; Nagu, A.; David Raju, B.; Rama Rao, K. S. published an article about the compound: Picolinamide( cas:1452-77-3,SMILESS:O=C(N)C1=NC=CC=C1 ).Reference of Picolinamide. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1452-77-3) through the article.
The present work is aimed to produce di-Me carbonate by coupling of CH3OH and CO2 with 2-cyanopyridine over ZnO-CeO2 catalysts prepared by co-precipitation method. These catalysts were characterized by XRD, TEM, UV-Vis DRS, BET surface area, CO2 and NH3-TPD techniques and applied for the titled reaction. Among the investigated catalysts 10ZnO-90CeO2 catalyst with CeO2 crystallite size 8.0 nm exhibited 96% conversion of methanol with 99% selectivity to di-Me carbonate. The superior catalytic activity is a unified effect of crystalline size of CeO2 and presence of an optimum number of acidic and basic sites. This protocol offers enhanced conversion of methanol with the simultaneous conversion of 2-cyanopyridine into 2-picolinamide by removing water mols. formed in the reaction.
After consulting a lot of data, we found that this compound(1452-77-3)Reference of Picolinamide can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem