The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Picolinamide( cas:1452-77-3 ) is researched.Reference of Picolinamide.Guerriero, Antonella; Peruzzini, Maurizio; Gonsalvi, Luca published the article 《Synthesis of New Ruthenium-CAP Complexes and Use as Catalysts for Benzonitrile Hydration to Benzamide》 about this compound( cas:1452-77-3 ) in European Journal of Inorganic Chemistry. Keywords: ruthenium triazaphosphatricyclotridecane complex preparation hydration catalyst. Let’s learn more about this compound (cas:1452-77-3).
The new bimetallic [Ru2(μ-Cl)3(CAP)6]Cl (1) and monometallic cis,cis,trans-[RuCl2(dmso-S)2(CAP)2] (2) complexes, bearing the water soluble cage-like phosphine CAP (1,4,7-triaza-9-phosphatricyclo[5.3.2.1]tridecane), were synthesized and characterized in solution by NMR spectroscopy and ESI-MS spectrometry. The complexes, endowed with high solubility and stability in water, were applied as catalysts for the proof-of-concept hydration of benzonitrile to benzamide in neat water at 100°C, achieving high conversions with only 1 mol % of catalyst, both in single runs and in catalyst recycling experiments
The article 《Synthesis of New Ruthenium-CAP Complexes and Use as Catalysts for Benzonitrile Hydration to Benzamide》 also mentions many details about this compound(1452-77-3)Reference of Picolinamide, you can pay attention to it, because details determine success or failure
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem