Lee, Wongyu; Kim, Dongwook; Seo, Sangwon; Chang, Sukbok published the artcile< Photoinduced α-C-H Amination of Cyclic Amine Scaffolds Enabled by Polar-Radical Relay>, Product Details of C14H18BrNO2, the main research area is cyclic amine photoinduced amination regioselective polar radical relay; Amination; Amines; Radicals; Reaction Mechanisms; Sustainability.
Herein, a polar-radical relay strategy for α-C-H amination of cyclic amines with N-chloro-N-sodio-carbamates is reported. The relay is initiated by in situ generation of a cyclic iminium intermediate using N-iodosuccinimide oxidant as an initiator, which then operates through a series of polar (addition and elimination) and radical (homolysis, hydrogen- and halogen atom transfer) reactions to enable the challenging C-N bond formation in a controlled manner. A broad range of α-amino cyclic amines were readily accessed with excellent regioselectivity, and the superb applicability was further demonstrated by functionalization of biol. relevant compounds
Angewandte Chemie, International Edition published new progress about Aminals Role: SPN (Synthetic Preparation), PREP (Preparation). 893566-75-1 belongs to class tetrahydroisoquinoline, and the molecular formula is C14H18BrNO2, Product Details of C14H18BrNO2.
Referemce:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem