Chachoyan, A. A. et al. published their research in Biologicheskii Zhurnal Armenii in 1972 | CAS: 2328-12-3

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (cas: 2328-12-3) belongs to tetrahydroisoquinoline derivatives. Tetrahydroisoquinoline, as a secondary amine, tetrahydroisoquinoline has weakly basic properties and forms salts with strong acids. An oxidative C1 arylation of tetrahydroisoquinolines with aryl Grignard reagents is mediated by diethyl azodicarboxylate (DEAD). This C-H activation under metal-free conditions delivers target compounds, including some naturally occurring alkaloids, in good yields.COA of Formula: C11H16ClNO2

Antineoplastic activity of some tetrahydroisoquinoline derivatives was written by Chachoyan, A. A.;Garibdzhanyan, B. T.;Markaryan, E. Z.. And the article was included in Biologicheskii Zhurnal Armenii in 1972.COA of Formula: C11H16ClNO2 This article mentions the following:

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-HCl (I) [2328-12-3] and similar compounds inhibited by 60-79% the growth of sarcoma 45 in rats. The compound had little or no activity against Walker carcinosarcoma or Ehrlich ascites carcinoma. In the experiment, the researchers used many compounds, for example, 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (cas: 2328-12-3COA of Formula: C11H16ClNO2).

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (cas: 2328-12-3) belongs to tetrahydroisoquinoline derivatives. Tetrahydroisoquinoline, as a secondary amine, tetrahydroisoquinoline has weakly basic properties and forms salts with strong acids. An oxidative C1 arylation of tetrahydroisoquinolines with aryl Grignard reagents is mediated by diethyl azodicarboxylate (DEAD). This C-H activation under metal-free conditions delivers target compounds, including some naturally occurring alkaloids, in good yields.COA of Formula: C11H16ClNO2

Referemce:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem