Ring-opening reactions of N-aryl-1,2,3,4-tetrahydroisoquinolines: synthesis of novel isoquino[2,1-a][3,1]benzoxazine derivatives was written by Stanforth, Stephen P.. And the article was included in Tetrahedron in 2000.HPLC of Formula: 2328-12-3 This article mentions the following:
The aldehydes 2,4-AcOCH2(O2N)C6H3NHCH2CH2C6H2R2CHO-4,5,2 [I, R = H, OMe] were prepared by treatment of the corresponding 1,2,3,4-tetrahydroisoquinolines with N-bromosuccinimide (NBS). Basic hydrolysis of I gave the 4bH,6H-isoquino[2,1-a][3,1]benzoxazine derivatives An ethoxy derivative was obtained directly from the reaction of the tetrahydroisoquinolines with NBS. In the experiment, the researchers used many compounds, for example, 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (cas: 2328-12-3HPLC of Formula: 2328-12-3).
6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (cas: 2328-12-3) belongs to tetrahydroisoquinoline derivatives. Tetrahydroisoquinoline, as a secondary amine, tetrahydroisoquinoline has weakly basic properties and forms salts with strong acids. Like other secondary amines, tetrahydroisoquinoline can be oxidized to the corresponding nitrone using hydrogen peroxide, catalyzed by selenium dioxide.HPLC of Formula: 2328-12-3
Referemce:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem