Application of 22990-19-8, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 22990-19-8, Name is 1-Phenyl-1,2,3,4-tetrahydroisoquinoline, molecular formula is C15H15N. In a Patent£¬once mentioned of 22990-19-8
thorley that new process for the preparation of intermediates (by machine translation)
The invention belongs to the field of medicine, in particular relates to a new process for the preparation of intermediates thorley that. The 2-halo benzophenoneoxime protection of the carbonyl group, n-butyl aldehyde after the lithium pulls out the bromine on, then with nitro methane condensation, catalytic hydrogenation reduction postacidification, then loop, passes through the reduction, chiral resolution alkaline hydrolysis after the new intermediate compounds by thorley I; the new intermediate thorley that the structural formula is: The invention utilizes the simple and easily obtained starting material, the production cost is reduced. This process route is advanced, mild reaction conditions, the reaction yield is high, little three waste, no expensive and toxic reagent, reaction solvent distillation can be applied mechanically, easy commercial production, has great social and economical benefits of environmental protection. (by machine translation)
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 22990-19-8. In my other articles, you can also check out more blogs about 22990-19-8
Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem