Some scientific research about 2-Phenyl-1,2,3,4-tetrahydroisoquinoline

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Direct oxidative phosphonylation of amines under metal-free conditions

Direct oxidation coupling of tertiary amines and dialkyl- or diphenyl-substituted phosphonates was developed. The reaction was mediated by DDQ under room temperature. Various phosphonates and N-aryl tetrahydroisoquinolines were tolerated in this reaction, and alpha-aminophosphonates were obtained with up to 99% yield.

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Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem