Brief introduction of 42923-77-3

The synthetic route of 42923-77-3 has been constantly updated, and we look forward to future research findings.

42923-77-3, 6-Methoxy-1,2,3,4-tetrahydroisoquinoline is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A solution of 6-methoxy- 1,2,3 ,4-tetrahydroisoquinoline (200 mg, 1.23 mmol) in HBr (3.16 g, 47% wt. in H20, 18.4 mmol) was stirred at 100 C overnight. After the reaction wascompleted, the mixture was concentrated in vacuo and triturated with EtOAc. The mixture wasfiltered and the solid was collected and dried in vacuo to give 1,2,3,4-tetrahydroisoquinolin-6- ol;hydrobromide (170 mg, 93%) as a brown solid. MS obsd. (ESIj [(M+H)]: 150.

The synthetic route of 42923-77-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; FENG, Song; LIANG, Chungen; LIU, Yongfu; TAN, Xuefei; WU, Jun; WANG, Jianping; (134 pag.)WO2020/79106; (2020); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem