Simple exploration of 2-Phenyl-1,2,3,4-tetrahydroisoquinoline

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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 2-Phenyl-1,2,3,4-tetrahydroisoquinoline. Introducing a new discovery about 3340-78-1, Name is 2-Phenyl-1,2,3,4-tetrahydroisoquinoline

A unique combined source of “cN” from 1,2-dichloroethane and TMSN3 in the copper-catalyzed cyanation of a C(sp3)-H bond adjacent to a nitrogen atom

A novel combined metal-free “CN” source from trimethylsilyl azide and 1,2-dichloroethane has been developed and successfully applied to copper-catalyzed oxidative cyanation of alpha-C-H tertiary amines for the synthesis of C1-cyanation tetrahydroisoquinoline derivatives with good to excellent yields for the first time.

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Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem