Synthetic Route of 57196-62-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.57196-62-0, Name is 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride, molecular formula is C10H14ClNO. In a Article，once mentioned of 57196-62-0
Structure-activity study on a series of alpha-glutamic acid scaffold based compounds as new ADAMTS inhibitors
A series of alpha-glutamic acid scaffold based 4-(benzamido)-4-(1,3,4- oxadiazol-2-yl) butanoic acids were designed and synthesized as new ADAMTS inhibitors. The compounds dose-dependently inhibited the enzymatic activities of ADAMTS-4 and ADAMTS-5. One of the most active compound 2h potently inhibited ADAMTS-4 and ADAMTS-5 with IC50 values of 1.2 and 0.8 muM, respectively. These inhibitors may serve as new lead compounds for further development of therapeutics to treat osteoarthritis.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 57196-62-0, and how the biochemistry of the body works.Synthetic Route of 57196-62-0
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem