The tetrahydroisoquinoline compound, name is 6-Methoxy-1,2,3,4-tetrahydroisoquinoline,cas is 42923-77-3, mainly used in chemical industry, its synthesis route is as follows.
General procedure: 1,2,3,4-Tetra-hydroisoquinoline(67 mg, 0.5 mmol), compound 11a (125 mg, 0.5 mmol),and potassium carbonate (207 mg, 1.5 mmol) were added to N,Ndimethylformamide,and the mixture was stirred at 100 C for12 h. After the reaction was completed, the mixture was extractedwith EtOAc, washed with water, brine, and dried over Na2SO4. Theorganic phase was concentrated in vacuo. The residues were purifiedby flash column chromatography (EtOAc/hexane = 1:3) to givecompound 3a (90 mg, 52%) as a white solid.
42923-77-3, As the rapid development of chemical substances, we look forward to future research findings about 42923-77-3
Reference£º
Article; Zhao, Chao; Choi, You Hee; Khadka, Daulat Bikram; Jin, Yifeng; Lee, Kwang-Youl; Cho, Won-Jea; Bioorganic and Medicinal Chemistry; vol. 24; 4; (2016); p. 789 – 801;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem