Chemical Research Letters, May 2021. HPLC of Formula: C15H15N, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.118864-75-8, Name is (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, molecular formula is C15H15N. In a Patent，once mentioned of 118864-75-8
The invention discloses a method of post-processing of the new thorley that, including the synthesis of new thorley thattotal fluid dropping slowly in strengthening acid, adjusting the pH value to 1.0-2.0 temperature after, add water using the extractant; after lowering the aqueous phase by adding saturated sodium carbonate solution to the alkaline, then adding dichloromethane sub-time extraction, extract use of water washing, by adding desiccant drying, position of; the evaporation in the low temperature position to the oily substance solly that our novel alkali. This invention, through optimization of the post-treatment process, the alkali treatment process after new thorley that steps in the use of only two kinds of solvent ISO-propyl ether and dichloromethane, type of the solvent is reduced, it is easy to operate and recycled, the cost is greatly saved. In the hydrochloric acid solly the new return alkali process are not used in a strong base or strong acid, using the saturated NaCO3 solution, the reaction is more moderate, is beneficial to control the temperature, the more important thing is the generation of the isomer is greatly reduced, so that the non-(1S, 3R) isomer of a reduced content of configuration. (by machine translation)
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 118864-75-8, help many people in the next few years.HPLC of Formula: C15H15N
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem