Research speed reading in 2021. Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent，Which mentioned a new discovery about COA of Formula: C9H10N2O2, molcular formula is C9H10N2O2, introducing its new discovery. , COA of Formula: C9H10N2O2
Two series of 2-butyl-8-azaspiro[5,4]decane-7,9-dione (a) and N-phthalimidobutyl (b) derivatives of 1,2,3,4-tetrahydroisoquinoline (THIQ) were synthesized. The impact of substituent variations in the aromatic part of the THIQ moiety on 5-HT1A and 5-HT2A receptor affinities, as well as in vivo functional properties of the investigated compounds are discussed. It was found that those modifications improved 5-HT2A receptor affinity, but also slightly reduced the binding affinity for 5-HT1A receptors (in comparison with the unsubstituted THIQ derivatives 3a and 3b). The most active compound (8-Br,5-OCH3-THIQ – 8a) showed features of a 5-HT1A (postsynaptic)/5-HT2A receptor antagonist. Additionally, all chloro derivatives with high and equal affinity for 5-HT1A receptors revealed different functional properties, i.e. an agonistic activity of presynaptic 5-HT1A receptors (4a) and a partial agonistic activity of postsynaptic 5-HT1A receptors (4a, 6a) or an antagonistic activity of postsynaptic ones (5a).
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C9H10N2O2, you can also check out more blogs about42923-79-5
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem