Research speed reading in 2021. Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent，Which mentioned a new discovery about name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline, molcular formula is C11H15NO2, introducing its new discovery. , name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline
A series of novel indole-based analogs were prepared and their affinities for sigma receptors were determined using in vitro radioligand binding assays. The results of this study identified several compounds with nanomolar sigma-2 affinity and significant selectivity over sigma-1 receptors. In particular, 2-(4-(3-(4-fluorophenyl)indol-1-yl)butyl)-6,7-dimethoxy-1,2,3, 4-tetrahydroisoquinoline (9f) was found to display high affinity at sigma-2 receptors with good selectivity (sigma-1/sigma-2 = 395). The pharmacological binding profile for this compound was established with other relevant non-sigma sites.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 1745-07-9, help many people in the next few years.name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline
Reference：
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem