The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Coupling of CH3OH and CO2 with 2-cyanopyridine for enhanced yields of dimethyl carbonate over ZnO-CeO2 catalyst》. Authors are Challa, Prathap; Venkata Rao, M.; Nagaiah, P.; Nagu, A.; David Raju, B.; Rama Rao, K. S..The article about the compound:Picolinamidecas:1452-77-3,SMILESS:O=C(N)C1=NC=CC=C1).Electric Literature of C6H6N2O. Through the article, more information about this compound (cas:1452-77-3) is conveyed.
The present work is aimed to produce di-Me carbonate by coupling of CH3OH and CO2 with 2-cyanopyridine over ZnO-CeO2 catalysts prepared by co-precipitation method. These catalysts were characterized by XRD, TEM, UV-Vis DRS, BET surface area, CO2 and NH3-TPD techniques and applied for the titled reaction. Among the investigated catalysts 10ZnO-90CeO2 catalyst with CeO2 crystallite size 8.0 nm exhibited 96% conversion of methanol with 99% selectivity to di-Me carbonate. The superior catalytic activity is a unified effect of crystalline size of CeO2 and presence of an optimum number of acidic and basic sites. This protocol offers enhanced conversion of methanol with the simultaneous conversion of 2-cyanopyridine into 2-picolinamide by removing water mols. formed in the reaction.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem