Safety of cis-Dichlorobis(pyridine)platinum(II). So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: cis-Dichlorobis(pyridine)platinum(II), is researched, Molecular C10H10Cl2N2Pt, CAS is 15227-42-6, about Suppression of growth by platinum(II) complexes in relation to their structure.
Structure-activity studies with 17 Pt-containing complexes showed a correlation between the ability of these complexes to inhibit cell division in corn roots and their known antitumor activities. For the more active compounds C90 (90% suppression of root growth rate) for 3 days was 3 × 10-6M, close to the corresponding amount for highly active inhibitors of other chem. classes. Possible use of the root growth rate to study the biol. activity of Pt-containing complexes is suggested. Structure-activity relations were discussed.
In some applications, this compound(15227-42-6)Safety of cis-Dichlorobis(pyridine)platinum(II) is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem