Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Chinese Chemical Letters called Silica supported potassium oxide catalyst for dehydration of 2-picolinamide to form 2-cyanopyridine, Author is Li, Yamei; Zhao, Yujun; Wang, Shengping; Ma, Xinbin, which mentions a compound: 1452-77-3, SMILESS is O=C(N)C1=NC=CC=C1, Molecular C6H6N2O, Name: Picolinamide.
The dehydration of 2-picolinamide to produce 2-cyanopyridine was investigated thoroughly using silica supported potassium oxide as a heterogeneous catalyst. Both large sp. surface area and pore size of SiO2 (B) contributed to the favorable catalytic performance for the synthesis of 2-CP. In addition, the yield of 2-CP showed the linear relationship with the amounts of medium basicity of the catalysts, demonstrating that medium basic sites were the active sites of silica supported potassium oxide catalysts. The catalysts were further characterized by XRD and FT-IR to clarify the active species. The results indicated the Si-O-K group produced by the reaction of K2CO3 with Si-OH was the active species, which was further evidenced by the adjustment of the amount of Si-OH by silylation and hydroxylation procedure.
From this literature《Silica supported potassium oxide catalyst for dehydration of 2-picolinamide to form 2-cyanopyridine》,we know some information about this compound(1452-77-3)Name: Picolinamide, but this is not all information, there are many literatures related to this compound(1452-77-3).
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem