Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-Dichlorobis(pyridine)platinum(II), is researched, Molecular C10H10Cl2N2Pt, CAS is 15227-42-6, about Synthesis of potential platinum(II) antitumor complexes: complexes containing bidentate pyridyl and imidazolyl donors.Synthetic Route of C10H10Cl2N2Pt.
PtLCl2 [L = di-2-pyridylmethane, 3,3-bis(2-pyridyl)pentane, 2-(2-pyridyl)imidazole (I), N-methyl-2-(2-pyridyl)imidazole] were prepared and characterized by chem. anal., elec. conductivity, IR spectra, and inhibitory effects on cultures of L1210 mouse leukemia cells. The complex with L = I gave a 50% inhibiting dose similar to that of cis-Pt(NH3)2Cl2 and below the values of the other complexes; this suggests that further tests with tumor-bearing animals is warranted for this I complex with Pt.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem