Name is 7-Nitro-1,2,3,4-tetrahydroisoquinoline, as a common heterocyclic compound, it belongs to tetrahydroisoquinoline compound, and cas is 42923-79-5, its synthesis route is as follows.,42923-79-5
A mixture of 7-nitro-l,2,3,4-tetrahydro-isoquinoline(1.5g, 8.38 mmole) and 10% Pd/C (300 mg) in diethyleneglycol (5 mL) was reacted in a Smith Synthesizer undermicrowave radiation at 220 2C for 25 min. The resultingmixture was diluted with MeOH and filtered. The filtrate wasconcentrated and diluted with CH2C12, washed with sat. aq.NH4C1 and dried over Na2S04. After filtration andconcentration, the title compound was isolated through flashchromatography (eluted with CH2Cl2:MeOH 9:1) as an orangesolid. MS: (ES+) 145(M+H). Calc’d. for C9H8N2 – 144.07.
With the complex challenges of chemical substances, we look forward to future research findings about 7-Nitro-1,2,3,4-tetrahydroisoquinoline
Reference£º
Patent; AMGEN INC.; WO2006/12374; (2006); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem