So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Vereshchagin, Anatoly N.; Gordeeva, Alexandra M.; Frolov, Nikita A.; Proshin, Pavel I.; Hansford, Karl A.; Egorov, Mikhail P. researched the compound: 1-Bromoundecane( cas:693-67-4 ).Application In Synthesis of 1-Bromoundecane.They published the article 《Synthesis and Microbiological Properties of Novel Bis-Quaternary Ammonium Compounds Based on Biphenyl Spacer》 about this compound( cas:693-67-4 ) in European Journal of Organic Chemistry. Keywords: quaternary ammonium biphenyl compound preparation antibacterial antifungal antitumor human. We’ll tell you more about this compound (cas:693-67-4).
Novel gemini (tail-head-spacer-head-tail) bis-quaternary ammonium compounds (bis-QACs) I (Hal = Cl, Br, I; n = 7, 8, 9, etc.) with a biphenyl spacer between two pyridinium heads were synthesized and compared with commonly used antiseptics such as benzalkonium chloride (BAC) and chlorhexidine digluconate (CHG). The series of compounds showed high inhibitory activity against five bacterial strains and two fungi. The compounds, which contain C8H17-C10H21 aliphatic tails were best within the series. A counterion change does not affect MIC in general. Cytotoxicity on human embryonic kidney cells and haemolysis were also investigated. Among the bis-QACs, cytotoxic effect was lower for I (Hal = Br; n = 12), which is the closest structural analog of BAC.
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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem