The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Picolinamide(SMILESS: O=C(N)C1=NC=CC=C1,cas:1452-77-3) is researched.Related Products of 693-67-4. The article 《Design of organoruthenium complexes for nanoparticle functionalization》 in relation to this compound, is published in Journal of Organometallic Chemistry. Let’s take a look at the latest research on this compound (cas:1452-77-3).
In recent years, extensive research efforts have been focused on loading metal complexes onto macromol. systems such as nanoparticles. We report a ligand with a catechol group based on a picolinamide which allows for coordination to organoruthenium moieties while the catechol group remains available for loading on nanoparticles as delivery vehicles towards tumors. All the compounds were characterized with standard anal. methods and the mol. structure of the ligand 1, and its Ru complexes 1a and 1b were determined by X-ray diffraction anal. The crystal structure of 1a and 1b showed pseudo-tetrahedral geometry of the Ru center with “”piano-stool”” conformation and 1 coordinated as an N,O-bidentate ligand, however, the latter depending on the reaction conditions employed. The Ru complexes 1a-1c were effectively loaded on magnetite nanoparticles as characterized by inductively-coupled plasma mass spectrometry (ICP-MS), transmission electron microscopy (TEM) and Fourier transform IR spectroscopy (FTIR).
In addition to the literature in the link below, there is a lot of literature about this compound(Picolinamide)Name: Picolinamide, illustrating the importance and wide applicability of this compound(1452-77-3).
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem